Linifanib

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Product name:Linifanib
CAS
: 796967-16-3
Molecular Formula: C21H18FN5O
Molecular weight:375.405
Density:1.424g/cm3
Melting point:180-183°C
Use :Linifanib is a structurally novel, potent inhibitor of receptor tyrosine kinases (RTK), vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGF receptor beta (PDGFR-β), KDR, and colony stimulating factor 1 receptor (CSF-1R), respectively.

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