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Ciclopirox is a topical antifungal

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Ciclopirox is a new broad-spectrum topical antifungal drug developed by the Federal German Pharmaceuticals. The mechanism of action is to alter the integrity of the fungal cell membrane, cause the outflow of intracellular substances, and block the uptake of proprotein precursors. It causes fungal cell death, has strong antibacterial and bactericidal effects on skin sputum, yeast, mold, etc., and has strong permeability. At higher concentrations, it can also inhibit certain actinomycetes, Gram-positive and Gram-negative bacteria, Mycoplasma, Chlamydia, Trichomonas, Trichomonas vaginalis and Pseudomonas aeruginosa.<BR>Compared with imidazole antifungal drugs, ciclopirox has a strong penetrating power on the stratum corneum on which the skin fungus lives, so it has significant antibacterial activity against deep fungus of the stratum corneum, such as hyperthyroidism.<BR>Clinically, ciclopirox is mainly used for fungal infections of superficial skin, such as body lice, athlete's foot, femoral hernia, hand and ankle (especially keratinized thickening), tinea versicolor, cutaneous candidiasis, Candida albicans And the treatment of hyperthyroidism.